NAD+ IV and Long COVID

Aug 05, 2022

What is NAD+?

NAD is the abbreviation for a compound called nicotinamide adenine dinucleotide. NAD+, a form of NAD, is responsible for many of these biological functions. In addition to the natural decline of NAD+ levels that occurs with aging, many disease states associated with increased oxidative stress cause a reduction of NAD+ levels (28).


Reduced levels of NAD+ have been shown to cause altered metabolic states and increased disease susceptibility. Research suggests these consequences may contribute to the extensive biological abnormalities seen across the SARS-CoV-2 disease spectrum (32). Early data indicate that NAD+ repletion therapy may reduce symptoms of long COVID (33).

How does NAD+ IV Infusion Therapy help reduce long COVID Symptoms?

Enzymes are a protein that speed up chemical reactions in the body. Many enzymes and proteins depend on NAD+ to carry out their respective functions.


When a person’s cells become infected with SARS-CoV-2, the virus that causes COVID and long COVID, the composition of enzymes produced by the cell’s protein synthesizing machinery drastically changes. Recent research has shown that the SARS-CoV-2 virus stimulates the infected cells to increase the synthesis of NAD+-consuming enzymes which preferentially provide NAD+ to viral activities (35-37). The NAD+-consuming enzymes which become upregulated in SARS-CoV-2 infection cause a severe depletion of available NAD+ (36-37). Without an adequate supply of NAD+, the NAD+-dependent enzymes of the interferon system cannot properly function, leading to impaired antiviral activity (34-37).


Physician-guided intravenous administration of NAD+ may safely provide direct and effective symptom relief of long COVID symptoms involving NAD+-depletion.

How does NAD+ IV Infusion Therapy help reduce long COVID Symptoms?

NAD+ can be administered orally or intravenously. Prior to your infusion, you will have a consultation with your physician, who will carefully consider your medical history and present symptoms to determine if you are a candidate for NAD+ IV Infusion Therapy.


During a NAD+ IV Infusion treatment, one of our highly experienced staff members will place an IV in your arm or hand, which will remain throughout the duration of the therapy. Over the course of 45 minutes to 4 hours, NAD+ will be administered through an IV drip with normal saline.

Hudson Medical + Wellness. (2022, March 16). NAD+ IV & long covid. Hudson Medical + Wellness. Retrieved August

5, 2022, from https://hudsonmedical.com/articles/nad-iv-long-covid/#:~:text=NAD%2B%20supplementation%20has%20been%20shown,symptoms%20involving%20NAD%2B%2Ddepletion 

health promotion and disease prevention
By Leah Carrington APRN 31 Jan, 2021
Both health promotion and disease prevention focus on better outcomes and quality of life, and in most cases, both are uses simultaneously to promote a healthy individual and community. However, the difference is when the focus is carried out.
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